In this episode, we explore an innovative prosthesis driven by the nervous system that helps people with amputations walk naturally and discover how this cutting-edge technology is transforming mobility and enhancing the quality of life for amputees by restoring a natural gait.

Podcast: Bionics Help Amputees Take Big Strides Forward

This article was discussed in our <a href="https://www.wevolver.com/profile/the.next.byte" rel="noopener noreferrer" target="_blank">Next Byte podcast</a>.&nbsp;<iframe height="200px" width="100%" frameborder="no" scrolling="no" seamless="" src="https://player.simplecast.com/ceb16e69-0075-4e23-97b8-f679ee5b172e?dark=false" class="fr-draggable" data-gtm-yt-inspected-24="true" data-lf-form-tracking-inspected-kn9eq4roawkarlvp="true" data-lf-yt-playback-inspected-kn9eq4roawkarlvp="true" data-lf-vimeo-playback-inspected-kn9eq4roawkarlvp="true"></iframe> The full article will continue below.<hr>State-of-the-art prosthetic limbs can help people with amputations achieve a natural walking gait, but they don’t give the user full neural control over the limb. Instead, they rely on robotic sensors and controllers that move the limb using predefined gait algorithms.Using a new type of surgical intervention and neuroprosthetic interface, MIT researchers, in collaboration with colleagues from Brigham and Women’s Hospital, have shown that a natural walking gait is achievable using a prosthetic leg fully driven by the body’s own nervous system. The surgical amputation procedure reconnects muscles in the residual limb, which allows patients to receive “proprioceptive” feedback about where their prosthetic limb is in space.In a study of seven patients who had this surgery, the MIT team found that they were able to walk faster, avoid obstacles, and climb stairs much more naturally than people with a traditional amputation.<iframe width="640" height="360" src="https://www.youtube.com/embed/fKdnu50Nx-8?&amp;wmode=opaque&amp;rel=0&amp;enablejsapi=1&amp;origin=https://www.wevolver.com" frameborder="0" allowfullscreen="" class="fr-draggable" data-lf-form-tracking-inspected-kn9eq4roawkarlvp="true" data-lf-yt-playback-inspected-kn9eq4roawkarlvp="true" data-lf-vimeo-playback-inspected-kn9eq4roawkarlvp="true" data-gtm-yt-inspected-24="true" id="651131305" title="Helping people with amputation walk naturally">&nbsp;</iframe>“This is the first prosthetic study in history that shows a leg prosthesis under full neural modulation, where a biomimetic gait emerges.&nbsp;No one has been able to show this level of brain control that produces a natural gait, where the human’s nervous system is controlling the movement, not a robotic control algorithm,” says Hugh Herr,&nbsp;a professor of media arts and sciences, co-director of the K. Lisa Yang Center for Bionics at MIT, an associate member of MIT’s McGovern Institute for Brain Research, and the senior author of the new study.Patients also experienced less pain and less muscle atrophy following this surgery, which is known as the agonist-antagonist myoneural interface (AMI). So far, about 60 patients around the world have received this type of surgery, which can also be done for people with arm amputations.Hyungeun Song, a postdoc in MIT’s Media Lab, is the lead author of the <a href="https://www.nature.com/articles/s41591-024-02994-9" target="_blank">paper</a>, which appears today in Nature Medicine.<h2>Sensory feedback</h2>Most limb movement is controlled by pairs of muscles that take turns stretching and contracting. During a traditional below-the-knee amputation, the interactions of these paired muscles are disrupted. This makes it very difficult for the nervous system to sense the position of a muscle and how fast it’s contracting — sensory information that is critical for the brain to decide how to move the limb.People with this kind of amputation may have trouble controlling their prosthetic limb because they can’t accurately sense where the limb is in space. Instead, they rely on robotic controllers built into the prosthetic limb. These limbs also include sensors that can detect and adjust to slopes and obstacles.To try to help people achieve a natural gait under full nervous system control, Herr and his colleagues began developing the AMI surgery several years ago. Instead of severing natural agonist-antagonist muscle interactions, they connect the two ends of the muscles so that they still dynamically communicate with each other within the residual limb. This surgery can be done during a primary amputation, or the muscles can be reconnected after the initial amputation as part of a revision procedure.“With the AMI amputation procedure, to the greatest extent possible, we attempt to connect native agonists to native antagonists in a physiological way so that after amputation, a person can move their full phantom limb with physiologic levels of proprioception and range of movement,” Herr says.In a 2021 <a href="https://news.mit.edu/2021/surgery-control-prosthetic-limbs-0215" target="_blank">study</a>, Herr’s lab found that patients who had this surgery were able to more precisely control the muscles of their amputated limb, and that those muscles produced electrical signals similar to those from their intact limb.After those encouraging results, the researchers set out to explore whether those electrical signals could generate commands for a prosthetic limb and at the same time give the user feedback about the limb’s position in space. The person wearing the prosthetic limb could then use that proprioceptive feedback to volitionally adjust their gait as needed.In the new Nature Medicine study, the MIT team found this sensory feedback did indeed translate into a smooth, near-natural ability to walk and navigate obstacles.“Because of the AMI neuroprosthetic interface, we were able to boost that neural signaling, preserving as much as we could. This was able to restore a person's neural capability to continuously and directly control the full gait, across different walking speeds, stairs, slopes, even going over obstacles,” Song says.<h2>A natural gait</h2>For this study, the researchers compared seven people who had the AMI surgery with seven who had traditional below-the-knee amputations. All of the subjects used the same type of bionic limb: a prosthesis with a powered ankle as well as electrodes that can sense electromyography (EMG) signals from the tibialis anterior the gastrocnemius muscles. These signals are fed into a robotic controller that helps the prosthesis calculate how much to bend the ankle, how much torque to apply, or how much power to deliver.The researchers tested the subjects in several different situations: level-ground walking across a 10-meter pathway, walking up a slope, walking down a ramp, walking up and down stairs, and walking on a level surface while avoiding obstacles.In all of these tasks, the people with the AMI neuroprosthetic interface were able to walk faster — at about the same rate as people without amputations — and navigate around obstacles more easily. They also showed more natural movements, such as pointing the toes of the prosthesis upward while going up stairs or stepping over an obstacle, and they were better able to coordinate the movements of their prosthetic limb and their intact limb. They were also able to push off the ground with the same amount of force as someone without an amputation.“With the AMI cohort, we saw natural biomimetic behaviors emerge,” Herr says.&nbsp;“The cohort that didn’t have the AMI, they were able to walk, but the prosthetic movements weren’t natural, and their movements were generally slower.”These natural behaviors emerged even though the amount of sensory feedback provided by the AMI was less than 20 percent of what would normally be received in people without an amputation.“One of the main findings here is that a small increase in neural feedback from your amputated limb can restore significant bionic neural controllability, to a point where you allow people to directly neurally control the speed of walking, adapt to different terrain, and avoid obstacles,” Song says.“This work represents yet another step in us demonstrating what is possible in terms of restoring function in patients who suffer from severe limb injury. It is through collaborative efforts such as this that we are able to make transformational progress in patient care,” says Matthew Carty, a surgeon at Brigham and Women’s Hospital and associate professor at Harvard Medical School, who is also an author of the paper.Enabling neural control by the person using the limb is a step toward Herr’s lab’s goal of “rebuilding human bodies,” rather than having people rely on ever more sophisticated robotic controllers and sensors — tools that are powerful but do not feel like part of the user’s body.“The problem with that long-term approach is that the user would never feel embodied with their prosthesis. They would never view the prosthesis as part of their body, part of self,” Herr says. “The approach we’re taking is trying to comprehensively connect the brain of the human to the electromechanics.”The research was funded by the MIT K. Lisa Yang Center for Bionics and the Eunice Kennedy Shriver National Institute of Child Health and Human Development.<img src="https://images.wevolver.com/eyJidWNrZXQiOiJ3ZXZvbHZlci1wcm9qZWN0LWltYWdlcyIsImtleSI6ImZyb2FsYS8xNzIwNDIzMTQxODg1LV9NR185NjE2LTMuanBnIiwiZWRpdHMiOnsicmVzaXplIjp7IndpZHRoIjo5NTAsImZpdCI6ImNvdmVyIn19fQ==" style="width: 100%px;" class="fr-fic fr-dib">Credit: Jimmy Day, MIT Media Lab

“This is the first prosthetic study in history that shows a leg prosthesis under full neural modulation,” Hugh Herr says. Image: Courtesy of Hugh Herr and Hyungeun Song

A new surgical procedure gives people more neural feedback from their residual limb. With it, seven patients walked more naturally and navigated obstacles.

A prosthesis driven by the nervous system helps people with amputation walk naturally

In this episode, we discuss a breakthrough from ETH Zurich to mimic natural foot signals to the brain using state of the art neuroprosthetics. 

Podcast: Neuroprosthetics: The Next Step Towards Limb Reconstruction

This article was discussed in our <a href="https://www.wevolver.com/profile/the.next.byte" rel="noopener noreferrer" target="_blank">Next Byte podcast</a>.&nbsp;<iframe height="200px" width="100%" frameborder="no" scrolling="no" seamless="" src="https://player.simplecast.com/b5ad041a-a5dc-42cd-900b-390dca184186?dark=false" class="fr-draggable" data-lf-form-tracking-inspected-kn9eq4roawkarlvp="true" data-lf-yt-playback-inspected-kn9eq4roawkarlvp="true" data-lf-vimeo-playback-inspected-kn9eq4roawkarlvp="true"></iframe> The full article will continue below.<hr>A few years ago, a team of researchers working under Professor Stanisa Raspopovic at the ETH Zurich Neuroengineering Lab gained worldwide attention when they announced that their prosthetic legs had enabled amputees to feel sensations from this artificial body part for the first time. Unlike commercial leg prostheses, which simply provide amputees with stability and support, the ETH researchers’ prosthetic device was connected to the sciatic nerve in the test subjects’ thigh via implanted electrodes.This electrical connection enabled the neuroprosthesis to communicate with the patient’s brain, for example relaying information on the constant changes in pressure detected on the sole of the prosthetic foot when walking. This gave the test subjects greater confidence in their prosthesis – and it enabled them to walk considerably faster on challenging terrains. “Our experimental leg prosthesis succeeded in evoking natural sensations. That’s something current neuroprostheses are mainly unable to do; instead, they mostly evoke artificial, unpleasant sensations,” Raspopovic says.This is probably because today’s neuroprosthetics are using time-constant electrical pulses to stimulate the nervous system. “That’s not only unnatural, but also inefficient,” Raspopovic says. In a recently published paper, he and his team used the example of their leg prostheses to highlight the benefits of using naturally inspired, biomimetic stimulation to develop the next generation of neuroprosthetics.<h2>Model simulates activation of nerves in the sole</h2>To generate these biomimetic signals, Natalija Katic – a doctoral student in Raspopovic’s research group – developed a computer model called FootSim. It is based on data collected by collaborators in Canada, who recorded the activity of natural receptors, named mechanoreceptors, in the sole of the foot while touching different points on the feet of volunteers with a vibrating rod.The model simulates the dynamic behaviour of large numbers of mechanoreceptors in the sole of the foot and generates the neural signals that shoot up the nerves in the leg towards the brain – from the moment the heel strikes the ground and the weight of the body starts to shift forward to the outside of the foot until the toes push off the ground ready for the next step. “Thanks to this model, we can see how semsory receptors from the sole, and the connected nerves, behave during walking or running, which is experimentally impossible to measure” Katic says.<img src="https://images.wevolver.com/eyJidWNrZXQiOiJ3ZXZvbHZlci1wcm9qZWN0LWltYWdlcyIsImtleSI6ImZyb2FsYS8xNzA5ODI0NDc4NjY1LWltYWdlLmltYWdlZm9ybWF0LjEyODYuNDg4NzEzNzM4LmpwZyIsImVkaXRzIjp7InJlc2l6ZSI6eyJ3aWR0aCI6OTUwLCJmaXQiOiJjb3ZlciJ9fX0=" style="width: 100%px;" class="fr-fic fr-dib">Restoring natural sensory feedback results in functional and cognitive benefits for leg prosthesis users. (Photograph: Pietro Comaschi)Restoring natural sensory feedback results in functional and cognitive benefits for leg prosthesis users.&nbsp;(Photograph: Pietro Comaschi)<h2 id="isPasted">Information overload in the spinal cord</h2>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;&nbsp;To assess how closely the biomimetic signals calculated by the model correspond to the signals emitted by real neurons, Giacomo Valle – a postdoc in Raspopovic’s research group – worked with colleagues in Germany, Serbia and Russia on experiments with cats, whose nervous system processes movement in a similar way to that of humans. The experiments took place in 2019 at the Pavlov Institute of Physiology in St. Petersburg and were carried out in accordance with the relevant European Union guidelines.The researchers implanted electrodes, connecting some to the nerve in the leg and some to the spinal cord to discover how the signals are transmitted through the nervous system. When the researchers applied pressure to the bottom of the cat’s paw, thereby evoking the natural neural response that occurs when a cat takes a step, the peculiar pattern of activity recorded in the spinal cord did indeed resemble the patterns that were elicited in the spinal cord when the researchers stimulated the leg nerve with biomimetic signals.By contrast, the conventional approach of time-constant stimulation of the sciatic nerve in the cat’s thigh elicited a markedly different pattern of activation in the spinal cord. “This clearly shows that the commonly used stimulation methods cause the neural networks in the spine to be flooded with information,” Valle says. “This information overload could be the reason for the unpleasant sensations or paraesthesia reported by some users of neuroprosthetics,” Raspopovic adds.<h2>Learning the language of the nervous system</h2>In their clinical trial with leg amputees, the researchers were able to show that biomimetic stimulation is superior to time-constant stimulation. Their work clearly demonstrated how the signals that mimicked nature produced better results: not only were the test subjects able to climb steps faster, they also made fewer mistakes in a task that required them to climb the same steps while spelling words backwards. “Biomimetic neurostimulation allows subjects to concentrate on other things while walking,” Raspopovic says, “so we concluded that this type of stimulation is more naturally processed and less taxing on the brain.”Raspopovic, whose lab forms part of the ETH Institute of Robotics and Intelligent Systems, believes that these new findings are not only relevant to the limb prostheses he and his team have been working on for over half a decade. He argues that the need to move away from unnatural, time-constant stimulation towards biomimetic signals also applies to a whole series of other aids and devices, including spinal implants and electrodes for brain stimulation. “We need to learn the language of the nervous system,” Raspopovic says. “Then we’ll be able to communicate with the brain in ways it really understands.”<h2>Information overload in the spinal cord</h2>To assess how closely the biomimetic signals calculated by the model correspond to the signals emitted by real neurons, Giacomo Valle – a postdoc in Raspopovic’s research group – worked with colleagues in Germany, Serbia and Russia on experiments with cats, whose nervous system processes movement in a similar way to that of humans. The experiments took place in 2019 at the Pavlov Institute of Physiology in St. Petersburg and were carried out in accordance with the relevant European Union guidelines.The researchers implanted electrodes, connecting some to the nerve in the leg and some to the spinal cord to discover how the signals are transmitted through the nervous system. When the researchers applied pressure to the bottom of the cat’s paw, thereby evoking the natural neural response that occurs when a cat takes a step, the peculiar pattern of activity recorded in the spinal cord did indeed resemble the patterns that were elicited in the spinal cord when the researchers stimulated the leg nerve with biomimetic signals.By contrast, the conventional approach of time-constant stimulation of the sciatic nerve in the cat’s thigh elicited a markedly different pattern of activation in the spinal cord. “This clearly shows that the commonly used stimulation methods cause the neural networks in the spine to be flooded with information,” Valle says. “This information overload could be the reason for the unpleasant sensations or paraesthesia reported by some users of neuroprosthetics,” Raspopovic adds.<h2>Learning the language of the nervous system</h2>In their clinical trial with leg amputees, the researchers were able to show that biomimetic stimulation is superior to time-constant stimulation. Their work clearly demonstrated how the signals that mimicked nature produced better results: not only were the test subjects able to climb steps faster, they also made fewer mistakes in a task that required them to climb the same steps while spelling words backwards. “Biomimetic neurostimulation allows subjects to concentrate on other things while walking,” Raspopovic says, “so we concluded that this type of stimulation is more naturally processed and less taxing on the brain.”Raspopovic, whose lab forms part of the ETH Institute of Robotics and Intelligent Systems, believes that these new findings are not only relevant to the limb prostheses he and his team have been working on for over half a decade. He argues that the need to move away from unnatural, time-constant stimulation towards biomimetic signals also applies to a whole series of other aids and devices, including spinal implants and electrodes for brain stimulation. “We need to learn the language of the nervous system,” Raspopovic says. “Then we’ll be able to communicate with the brain in ways it really understands.”<hr><h2 id="isPasted">Reference</h2>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;&nbsp;Valle G, Katic Secerovic N, Eggemann D, Gorskii O, Pavlova N, Petrini FM, Cvancara P, Stieglitz T, Musienko P, Bumbasirevic M, Raspopovic S: Biomimetic computer-to-brain communication enhancing naturalistic touch sensations via peripheral nerve stimulation. Nature Communications, 20 February 2024, doi: <a href="https://doi.org/10.1038/s41467-024-45190-6" target="_blank">external page10.1038/s41467-024-45190-6</a>

ETH researchers have developed a prosthetic leg that communicates with the brain via natural signals. (Photograph: Keystone)

Prostheses that connect to the nervous system have been available for several years. Now, researchers at ETH Zurich have found evidence that neuroprosthetics work better when they use signals that are inspired by nature.

Bio-inspired neuroprosthetics: sending signals the brain can understand

This article was discussed in our <a href="https://www.wevolver.com/profile/the.next.byte" rel="noopener noreferrer" target="_blank">Next Byte podcast</a>.&nbsp;<iframe height="200px" width="100%" frameborder="no" scrolling="no" seamless="" src="https://player.simplecast.com/18c9c9fd-d774-46bc-87b8-fb1b0e7a5ae4?dark=false" class="fr-draggable" data-gtm-yt-inspected-9="true" data-lf-form-tracking-inspected-kn9eq4roawkarlvp="true" data-lf-yt-playback-inspected-kn9eq4roawkarlvp="true" data-lf-vimeo-playback-inspected-kn9eq4roawkarlvp="true"></iframe> The full article will continue below.<hr>Jellyfish can't do much besides swim, sting, eat, and breed. They don't even have brains. Yet, these simple creatures can easily journey to the depths of the oceans in a way that humans, despite all our sophistication, cannot.But what if humans could have jellyfish explore the oceans on our behalf, reporting back what they find? New research conducted at Caltech aims to make that a reality through the creation of what researchers call biohybrid robotic jellyfish. These creatures, which can be thought of as ocean-going cyborgs, augment jellyfish with electronics that enhance their swimming and a prosthetic "hat" that can carry a small payload while also making the jellyfish swim in a more streamlined manner.The work, published in the journal Bioinspiration &amp; Biomimetics, was conducted in the lab of John Dabiri (MS '03, PhD '05), the Centennial Professor of Aeronautics and Mechanical Engineering, and builds on his previous work augmenting jellyfish. Dabiri's goal with this research is to use jellyfish as robotic data-gatherers, sending them into the oceans to collect information about temperature, salinity, and oxygen levels, all of which are affected by Earth's changing climate."It's well known that the ocean is critical for determining our present and future climate on land, and yet, we still know surprisingly little about the ocean, especially away from the surface," Dabiri says. "Our goal is to finally move that needle by taking an unconventional approach inspired by one of the few animals that already successfully explores the entire ocean."<iframe width="640" height="360" src="https://www.youtube.com/embed/_ZfthP_7s5g?&amp;wmode=opaque&amp;rel=0&amp;enablejsapi=1&amp;origin=https://www.wevolver.com" frameborder="0" allowfullscreen="" class="fr-draggable" data-lf-form-tracking-inspected-kn9eq4roawkarlvp="true" data-lf-yt-playback-inspected-kn9eq4roawkarlvp="true" data-lf-vimeo-playback-inspected-kn9eq4roawkarlvp="true" data-gtm-yt-inspected-9="true" id="779481107" title="Robotic Jellyfish Explorers">&nbsp;</iframe>Media assets: Robotic Jellyfish ExplorersThroughout his career, Dabiri has looked to the natural world, jellyfish included, for inspiration in solving engineering challenges. This work began with early attempts by Dabiri's lab to develop a mechanical robot that swam like jellyfish, which have the most efficient method for traveling through water of any living creature. Though his research team succeeded in creating such a robot, that robot was never able to swim as efficiently as a real jellyfish. At that point, Dabiri asked himself, why not just work with jellyfish themselves?"Jellyfish are the original ocean explorers, reaching its deepest corners and thriving just as well in tropical or polar waters," Dabiri says. "Since they don't have a brain or the ability to sense pain, we've been able to collaborate with bioethicists to develop this biohybrid robotic application in a way that's ethically principled."Previously, Dabiri's lab implanted jellyfish with a kind of electronic pacemaker that controls the speed at which they swim. In doing so, they found that if they made jellyfish swim faster than the leisurely pace they normally keep, the animals became even more efficient. A jellyfish swimming three times faster than it normally would uses only twice as much energy.This time, the research team went a step further, adding what they call a forebody to the jellies. These forebodies are like hats that sit atop the jellyfish's bell (the mushroom-shaped part of the animal). The devices were designed by graduate student and lead author Simon Anuszczyk (MS '22), who aimed to make the jellyfish more streamlined while also providing a place where sensors and other electronics can be carried."Much like the pointed end of an arrow, we designed 3D-printed forebodies to streamline the bell of the jellyfish robot, reduce drag, and increase swimming performance," Anuszczyk says. "At the same time, we experimented with 3D printing until we were able to carefully balance the buoyancy and keep the jellyfish swimming vertically."To test the augmented jellies' swimming abilities, Dabiri's lab undertook the construction of a massive vertical aquarium inside Caltech's Guggenheim Laboratory. Dabiri explains that the three-story tank is tall, rather than wide, because researchers want to gather data on oceanic conditions far below the surface."In the ocean, the round trip from the surface down to several thousand meters will take a few days for the jellyfish, so we wanted to develop a facility to study that process in the lab," Dabiri says. "Our vertical tank lets the animals swim against a flowing vertical current, like a treadmill for swimmers. We expect the unique scale of the facility—probably the first vertical water treadmill of its kind—to be useful for a variety of other basic and applied research questions."<img src="https://images.wevolver.com/eyJidWNrZXQiOiJ3ZXZvbHZlci1wcm9qZWN0LWltYWdlcyIsImtleSI6ImZyb2FsYS8xNzA5NTIxNzc5NzI4LURhYmlyaS1MYWItTG9uZy1EaXN0YW5jZS1Td2ltbWluZ19Gb3JlYm9keTMubWF4LTE0MDB4ODAwLmpwZyIsImVkaXRzIjp7InJlc2l6ZSI6eyJ3aWR0aCI6OTUwLCJmaXQiOiJjb3ZlciJ9fX0=" style="width: 100%px;" class="fr-fic fr-dib">A biohybrid jellyfish descends through the three-story tank in which swimming tests were conducted. Credit: CaltechSwim tests conducted in the tank show that a jellyfish equipped with a combination of the swimming pacemaker and forebody can swim up to 4.5 times faster than an all-natural jelly while carrying a payload. The total cost is about $20 per jellyfish, Dabiri says, which makes biohybrid jellies an attractive alternative to renting a research vessel that can cost more than $50,000 a day to run."By using the jellyfish's natural capacity to withstand extreme pressures in the deep ocean and their ability to power themselves by feeding, our engineering challenge is a lot more manageable," Dabiri adds. "We still need to design the sensor package to withstand the same crushing pressures, but that device is smaller than a softball, making it much easier to design than a full submarine vehicle operating at those depths."I'm really excited to see what we can learn by simply observing these parts of the ocean for the very first time," he adds.Dabiri says future work may focus on further enhancing the bionic jellies' abilities. Right now, they can only be made to swim faster in a straight line, such as the vertical paths being designed for deep ocean measurement. But further research may also make them steerable, so they can be directed horizontally as well as vertically.The paper describing the work, "<a href="https://iopscience.iop.org/article/10.1088/1748-3190/ad277f" target="_blank">Electromechanical enhancement of live jellyfish for ocean exploration</a>," appears in the February 28 issue of Bioinspiration &amp; Biomimetics. Co-authors are Anuszczyk and Dabiri.

Jellyfish can't do much besides swim, sting, eat, and breed. They don't even have brains. Yet, these simple creatures can easily journey to the depths of the oceans in a way that humans, despite all our sophistication, cannot.

Building Bionic Jellyfish for Ocean Exploration

This article originally appeared in <a href="https://engineering.wustl.edu/news/2023/Brain-machine-interfaces-for-insects-to-study-principles-of-odor-guided-navigation.html" target="_blank" rel="noopener noreferrer">McKelvey School of Engineering</a> and has been republished with permission.<hr><iframe width="640" height="360" src="https://www.youtube.com/embed/dBNOGbF-e7E?&amp;wmode=opaque&amp;rel=0&amp;enablejsapi=1&amp;origin=https://www.wevolver.com" frameborder="0" allowfullscreen="" class="fr-draggable" data-lf-form-tracking-inspected-kn9eq4roawkarlvp="true" data-lf-yt-playback-inspected-kn9eq4roawkarlvp="true" data-lf-vimeo-playback-inspected-kn9eq4roawkarlvp="true"></iframe>The locust follows a pleasant scent on a treadmill. (Credit: Raman lab)The inviting smell of a freshly baked cookie immediately triggers a motor response to search for the source of that smell. Often the cookie can be easily found.This everyday event that we perform without a thought is an amazing feat that combines our superior ability to smell the cookie and computational prowess to determine the directions to move toward the cookie. Robots that possess similar capabilities are yet to be developed as the basic biological principles that are needed to perform this task are yet to be fully understood. &nbsp;The ability to study neural responses in behaving insects is essential to understanding the robust solutions biological systems have developed for several engineering problems. For example, locusts have survived for at least 8 million years — longer than humans have been on this planet — in nearly all parts of the earth. Their many remarkable capabilities include seeing, hearing and smelling things that humans cannot sense, jumping multiple times their body length, the uncanny ability to fly up to 100 kilometers a day, and switching between solitary and menacing swarms phases as needed for survival. They use these capabilities to find food, avoid predators, propagate their species, and do all things necessary to keep them alive. Researchers in the McKelvey School of Engineering at Washington University in St. Louis have long sought to understand the power of the locusts’ sensing, computing and locomotory capabilities.Barani Raman, professor of biomedical engineering in the McKelvey School of Engineering, is leading a multidisciplinary team to study how the locust brain transforms sensory input into behavior with a four-year, $4.3 million grant from the National Science Foundation’s Integrative Strategies for Understanding Neural and Cognitive Systems (NCS) program. The grant converges years of research in Raman’s lab with that of his longtime WashU collaborators, including Shantanu Chakrabartty, professor of electrical &amp; systems engineering, and Srikanth Singamaneni, professor of mechanical engineering &amp; materials science, as well as Alexandra Rutz, assistant professor of biomedical engineering, and Yehuda Ben-Shahar, professor of biology, also at WashU.<img src="https://s3-us-west-1.amazonaws.com/wevolver-project-images/froala%2F1697685410077-ezgif-5-9129b96817.jpg" style="width: 766px;" class="fr-fic fr-dib">Researchers in the McKelvey School of Engineering have long sought to understand the power of the locusts’ sensing, computing and locomotory capabilities. With a $4.3 million grant from the National Science Foundation, they will converge that research to develop a “cyborg,” or mobile robot or drone, that can mimic the locusts’ behaviors. (Credit: Raman lab)“Insects are an engineering marvel,” Raman said. “They possess diverse sensing modalities and locomotory responses yet contained in such a small package. We want to engineer tools to study the amazing capabilities of these relatively simpler organisms.”The research brings together Washington University’s strengths in neural engineering, integrated circuits, biomaterials, synthetic biology and genetic engineering to understand how the insects use olfactory cues to navigate toward an odor source, which could potentially be used for various applications, such as detecting gas left on in the kitchen or as the proverbial canary in the coal mine to test spaces for hazardous chemicals. In 2024, the team plans to launch the first-of-its-kind Center for Cyborg and Biorobotics Research (CyBoR) to formally conduct the research.&nbsp;The team plans to study the neural response in the locusts’ brains by having the locusts follow a specific odor on a specially built treadmill while walking on a foam ball and while flying in a wind tunnel. By studying their movements and neural activity in the brain in response to these odors, the team can process the information using a custom microchip to develop a “cyborg,” or mobile robot or drone, that can mimic the locusts’ behaviors. They also aim to augment the locusts’ ability to detect certain odors over others.“Nature already has endowed this organism with various capabilities, so why not understand and augment those capabilities using synthetic mechanisms?” asked Chakrabartty, whose expertise is in sensors and integrated circuits. “Ultimately, our goal is to design a completely synthetic system that has similar remarkable capabilities.”While the team has already joined forces to create recording instruments and nanomaterials to manipulate neural and behavioral responses, they will continue to improve on those as they develop the bio-hybrid and mobile robotic systems.&nbsp;“One of the important challenges in these studies is the limited stability of the neural recording and stimulation electrodes and interfaces over a long period,” said Singamaneni, whose expertise is in novel bio- and nanomaterials. “We aim to design and realize novel anti-inflammatory electrodes and biointerfaces that will enable stable long-term neural recording and stimulation.”Previously, <a href="https://engineering.wustl.edu/news/2016/Engineers-to-use-cyborg-insects-as-biorobotic-sensing-machines.html" target="_blank">the research team developed a miniature “backpack”</a> containing sensors that recorded the locusts’ brain activity when exposed to the odors. However, the existing backpack is too heavy for the locusts to wear while flying, so the team will work to reduce its weight.At Washington University, the research is underway in a state-of-the-art CyBoR facility that includes the habitat for the locusts, the treadmill, the wind tunnel, specialized microscopes, and space for visiting researchers as well as for visitors interested in learning about the insects. WashU students also will be included in the research as well as students from the community through various outreach programs.&nbsp;Other co-investigators include Alper Bozkurt, distinguished professor of electrical &amp; computer engineering at North Carolina State University, who will lead efforts on instrumentation for navigation control; Sawyer Fuller, assistant professor of mechanical engineering at the University of Washington, who will lead efforts to build miniaturized robots that incorporate both biological and engineering elements; and Nabil Imam, assistant professor of computational science and engineering at Georgia Tech, who will lead the development of neuromorphic algorithms and hardware in the bio-hybrid and robotic systems.

Barani Raman, professor of biomedical engineering in the McKelvey School of Engineering, is leading a multidisciplinary team to study how the locust brain transforms sensory input into behavior with a four-year, $4.3 million grant from the National Science Foundation’s Integrative Strategies for Understanding Neural and Cognitive Systems (NCS) program. 

Brain-machine interfaces for insects to study principles of odor-guided navigation

<div data-draftjs-conductor-fragment='{"blocks":[{"key":"74cni","text":"Authors Wim Christiaens | Quand Industries | Wim.Christiaens@quad-ind.com ","type":"unstyled","depth":0,"inlineStyleRanges":[],"entityRanges":[],"data":{}}],"entityMap":{},"VERSION":"9.14.3"}' id="isPasted">Authors Wim Christiaens | Quand Industries | &nbsp;Wim.Christiaens@quad-ind.com&nbsp;</div>Textiles are tactile, sensorial and visual. Qualities can be modified or even expanded when technology is added, transforming passive textiles into active and interactive devices, monitoring and detecting bodily functions due to their constant contact with our skin.&nbsp;<img src="https://images.wevolver.com/eyJidWNrZXQiOiJ3ZXZvbHZlci1wcm9qZWN0LWltYWdlcyIsImtleSI6ImZyb2FsYS8xNjk1MTM1MDU4ODI3LTMwNzQ1LmpwZyIsImVkaXRzIjp7InJlc2l6ZSI6eyJ3aWR0aCI6OTUwLCJmaXQiOiJjb3ZlciJ9fX0=" style="width: 532px;" class="fr-fic fr-dib"><h3>Printed electronics technology: the superior choice for smart textiles</h3>Printed electronics technology opens up possibilities that the older wired technologies simply cannot match.&nbsp;<ul><li>Thanks to their flexibility, stretchability and lightweight, printed electronics allow for smart garments that function as a second skin with a great level of comfort for its wearer.&nbsp;</li><li>Printed electronics are also more durable than traditional electronics and can withstand multiple washing cycles, crinkling, friction and sweating.&nbsp;</li><li>The lower production costs and easy scalability of printed electronics also stimulate the development of new (IoT) applications and a larger adoption of e-garments and smart fabrics in general, which can promote a healthier lifestyle and reduce the risk of disease, accidents and injuries in many industries.&nbsp;</li><li>Their integration is straightforward. After printing the sensors on TPU they can be transferred onto the textile material via hot press lamination. Both are well-established techniques. &nbsp; &nbsp;&nbsp;</li></ul><img src="https://images.wevolver.com/eyJidWNrZXQiOiJ3ZXZvbHZlci1wcm9qZWN0LWltYWdlcyIsImtleSI6ImZyb2FsYS8xNjk1MTM1MjQ3NDc4LWltYWdlMDAxLnBuZyIsImVkaXRzIjp7InJlc2l6ZSI6eyJ3aWR0aCI6OTUwLCJmaXQiOiJjb3ZlciJ9fX0=" style="width: 553px;" class="fr-fic fr-dib"><img src="https://s3-us-west-1.amazonaws.com/wevolver-project-images/froala%2F1699455670417-B-and-B-2024%28blog%29.jpg" style="width: 756px;" class="fr-fic fr-dib">Join us in Berlin and/or Boston and lets us RESHAPE the Future of Electronics, making it Additive, Sustainable, Hybrid, Wearable, and 3D - techblick.com<ul><li>Compared to traditional electronics manufacturing, printed electronics are easily scalable and low cost.&nbsp;</li><li>They are durable, precise, efficient and comfortable to wear.&nbsp;</li><li>They have excellent interconnectability. The PCB’s can be positioned in a remote spot, are small and don’t need much power to work. &nbsp; &nbsp; &nbsp;</li></ul><img src="https://images.wevolver.com/eyJidWNrZXQiOiJ3ZXZvbHZlci1wcm9qZWN0LWltYWdlcyIsImtleSI6ImZyb2FsYS8xNjk1MTk3OTk3Mjk4LVNjcmVlbnNob3QgMjAyMy0wOS0yMCAwOTE4MTcucG5nIiwiZWRpdHMiOnsicmVzaXplIjp7IndpZHRoIjo5NTAsImZpdCI6ImNvdmVyIn19fQ==" style="width: 686px;" class="fr-fic fr-dib"><a href="https://www.techblick.com/post/smart-textiles-monitoring-sensing-and-heating-technology-integrated-in-fabrics#viewer-71qek" target="_blank" rel="noopener noreferrer">Click here to watch the video</a> demonstration <hr><h3>Applications that change our lifestyle</h3>Athletic monitoring: Train smarter, not harderA wide range of smart sportswear (e.g. shirts, insoles, sports bras) track vital signs (via printed ECG or EMG sensors), core temperature, and biomechanics both during training and in the recovery phase. It helps athletes to enhance performance, ensure a healthy athletic growth, help reduce stress and prevent different types of injuries. &nbsp; &nbsp;Alleviating the healthcare and medical sectorSmart textiles serve as a functional and comfortable ‘wearable computer’ that help health care professionals by monitoring and communicating a patient's condition by detecting, storing, analysing, and transmitting physiological signals.Automotive and aerospaceIn the aerospace industry and in vehicle engineering, current applications focus on smart sensors integrated in interior fabrics and biometric monitoring for safety purposes. Information can provide insight into the driver's physical condition and level of fatigue, triggering haptic feedback through the steering wheel or warning alerts in the car's cockpit.&nbsp;Active workwearThe monitoring of vital signs of workers in demanding environments and high-risk industries has been made easier. In regulated industries where safety rules restrict workers from wearing devices, smart workwear can give insightful information about the condition of workers or machine operators that can be used to optimize their well-being, performance and productivity. Thermal workwear to dynamically regulate body temperature of workers in cold climates is another huge application domain.Textile-integrated flexible heaters&nbsp;There is a steep rise of interest is heating technology for garments. Stretchable printed electronics heaters make it easy to incorporate heat into comfortable, elegant, flexible, lightweight clothing. The high precision that can be achieved with screen-printed circuitry also makes it simpler to provide warmth exactly where required and avoid areas of the body which don’t need any additional heat.<div data-draftjs-conductor-fragment="{&quot;blocks&quot;:[{&quot;key&quot;:&quot;17kt9&quot;,&quot;text&quot;:&quot;Join us at TechBlick's Future of Electronics RESHAPED conference & tradeshow in Berlin on 17-18 OCT 2023 - www.techblick.com/electronicsreshaped. For special discounts on attendee passes please contact Wim.Christiaens@quad-ind.com &quot;,&quot;type&quot;:&quot;unstyled&quot;,&quot;depth&quot;:0,&quot;inlineStyleRanges&quot;:[{&quot;offset&quot;:0,&quot;length&quot;:107,&quot;style&quot;:&quot;{\&quot;FG\&quot;:\&quot;#424242\&quot;}&quot;},{&quot;offset&quot;:0,&quot;length&quot;:53,&quot;style&quot;:&quot;UNDERLINE&quot;},{&quot;offset&quot;:107,&quot;length&quot;:37,&quot;style&quot;:&quot;UNDERLINE&quot;},{&quot;offset&quot;:146,&quot;length&quot;:86,&quot;style&quot;:&quot;BOLD&quot;},{&quot;offset&quot;:146,&quot;length&quot;:86,&quot;style&quot;:&quot;{\&quot;FG\&quot;:\&quot;#dc3134\&quot;}&quot;}],&quot;entityRanges&quot;:[{&quot;offset&quot;:0,&quot;length&quot;:53,&quot;key&quot;:0},{&quot;offset&quot;:107,&quot;length&quot;:37,&quot;key&quot;:1}],&quot;data&quot;:{}}],&quot;entityMap&quot;:{&quot;0&quot;:{&quot;type&quot;:&quot;LINK&quot;,&quot;mutability&quot;:&quot;MUTABLE&quot;,&quot;data&quot;:{&quot;url&quot;:&quot;https://www.techblick.com/electronicsreshaped&quot;,&quot;target&quot;:&quot;_blank&quot;,&quot;rel&quot;:&quot;&quot;}},&quot;1&quot;:{&quot;type&quot;:&quot;LINK&quot;,&quot;mutability&quot;:&quot;MUTABLE&quot;,&quot;data&quot;:{&quot;url&quot;:&quot;https://www.techblick.com/electronicsreshaped&quot;,&quot;target&quot;:&quot;_blank&quot;,&quot;rel&quot;:&quot;&quot;}}},&quot;VERSION&quot;:&quot;9.14.3&quot;}" id="isPasted"><a data-hook="linkViewer" href="https://www.techblick.com/electronicsreshaped" target="_blank" rel="noopener noreferrer">Join us in Berlin and/or Boston and lets us RESHAPE the Future of Electronics, making it Additive, Sustainable, Hybrid, Wearable, and 3D - techblick.com</a></div><img src="https://s3-us-west-1.amazonaws.com/wevolver-project-images/froala%2F1699455718770-B-and-B-2024%28small-LinkedIn+for-email%29.jpg" style="width: 766px;" class="fr-fic fr-dib">

Textiles are tactile, sensorial and visual. Qualities can be modified or even expanded when technology is added, transforming passive textiles into active and interactive devices, monitoring and detecting bodily functions due to their constant contact with our skin. 

Smart Textiles: monitoring, sensing and heating technology integrated in fabrics

<h2 dir="ltr" id="isPasted">Tried and tested (and free)</h2>Biomimetics is the method by which scientists borrow successful ideas from nature to use in their own inventions. The advantage of this approach is that the solutions found among animals and plants are not subject to any patent. And over countless millennia, there are certain structures and mechanisms in nature that have allowed all sorts of living things to survive in various conditions. Thus, developers can rely on nature&rsquo;s best ideas, modify them as needed, and create robots that resemble beings we&rsquo;re already familiar with.<blockquote>&ldquo;For instance, there&rsquo;s a German company named Festo that specializes in various biomimetic solutions. They have a kangaroo robot that, just like the real thing, conserves energy after a jump and uses it for the next one. There are other notable inventions: the well-known Spot robot-dogs, worm-like medical robots, or even drug delivery bots modeled after fish. Some specialists develop mechanisms based on plant life &ndash; plantoids. But that&rsquo;s still a work in progress and it&rsquo;ll be some time before you can buy one in a store,&rdquo; explains Pavel Kovalenko, an associate professor at the Faculty of Control Systems and Robotics.</blockquote><h2 dir="ltr" id="isPasted">More ground to cover</h2>Nevertheless, the biomimetic method suffers from several limitations. Firstly, scientists have not been successful in recreating the principles or developing materials that would allow them to fully replicate certain species. Take geckos: these lizards&rsquo; paws are covered with microscopic adhesive hairs that can stick to any smooth vertical surface and traverse it. But researchers are yet to create a similar technology that would be suitable for industrial production.<blockquote>&ldquo;When we try to create the same product using nanolithography, the hairs come out different: not splayed like they should be, but rather conical or simply crudely shaped. Because of this, the adhesion is not adequate. In addition, artificial materials cannot self-clean and, therefore, lose their stickiness. It&rsquo;s like a piece of duct tape that you apply and tear off again and again,&rdquo; says Pavel Kovalenko.</blockquote>The second limitation of biomimetics is the scalability of natural mechanisms: as a rule, the ideas used at nanoscale are not always reproducible in macroscale. This forces researchers to look for other solutions to applied problems. For instance, instead of a robotic gecko, they will also create a snail that can climb vertical surfaces.Last but not least, for robots to function as animals, researchers have to truly synchronize their control system, its components, and parts of the robot. According to Pavel Kovalenko, this can be achieved when both the software and the engineering aspects of the robot are developed by a single team with a clear view of their final outcome.&nbsp;<h2 dir="ltr" id="isPasted">A robotic zoo at ITMO</h2>Despite all these challenges, students and graduates of ITMO&rsquo;s Faculty of Control Systems and Robotics are actively engaged in biomimetics, having already completed several stages of their research. First, they analyzed the behavior, body structure and functions of living organisms, and then based on this step decided which body parts they should recreate in their work. They have also selected flexible materials resembling existing animals. At the next stage, the researchers performed calculations, chose the digital components and motors for the robot, and developed the necessary software. As a result, they have already created several model robotic animals.For instance, ITMO graduate Georgy Larionenko developed a waterproof robotic fish with a moving tail that works on two magnets. A servomotor inside the waterproof body activates the first magnet, which in its turn activates the second one that is connected to the fluke. This way, by moving its tail in the water, the robotic fish can swim &ndash; both in fresh and salty water, as experiments have shown. The robot can be useful for gauging the parameters of the water and the ocean floor in various conditions, including in the arctic region.&nbsp;<iframe src="https://www.youtube.com/embed/fYqbsCFRuS0?&wmode=opaque&rel=0&enablejsapi=1&origin=https://www.wevolver.com" frameborder="0" allowfullscreen="" class="fr-draggable" data-lf-form-tracking-inspected-kn9eq4roawkarlvp="true" data-lf-yt-playback-inspected-kn9eq4roawkarlvp="true" style="width: 768px; height: 429px;"></iframe>A team of three graduates, Oksana Shuraeva, Anastasia Yusupova, and Anton Kovalenko, has developed a robotic snail. It can crawl down inclined surfaces by intermittently extending and retracting its &ldquo;paws,&rdquo; two spirals with plates attached to them. In order to guide the robot in the necessary direction, a servomotor, located in its shell, positions the snail&rsquo;s head at the needed angle, so that the rest of its body can follow suit. One application of this invention is window cleaning &ndash; the snail will leave a trail of detergent behind.Elizaveta Shelukhina, another ITMO graduate, wanted to make a device that will be protected from its environment. She could take inspiration from several animals, including turtles, hedgehogs, and armadillos, but eventually decided to settle on the latter, creating the concept for robotic armadillo. When the robot senses that something is falling on it or if someone kicks it, it rolls into a ball to protect its silicon insides. When the external influence ends, the robot unrolls back into its full length. Such robotic armadillos can come in handy in rescue missions, when there is a high risk of buildings collapsing.<img src="https://s3-us-west-1.amazonaws.com/wevolver-project-images/froala%2F1665655602540-1282503.jpg" style="width: 766px;" class="fr-fic fr-dib">Robotic snail. Image courtesy of the Faculty of Control Systems and Robotics&nbsp;<img src="https://s3-us-west-1.amazonaws.com/wevolver-project-images/froala%2F1665655652013-1282504.jpg" style="width: 766px;" class="fr-fic fr-dib">The snail&rsquo;s locomotion mechanism includes two spirals with plates attached to them. The spirals are activated by two D41AB12 DC motors and when climbing an inclined surface the snail&rsquo;s front part is controlled by an FS5106B servomotor. Image courtesy of the Faculty of Control Systems and Robotics&nbsp; &nbsp;<img src="https://s3-us-west-1.amazonaws.com/wevolver-project-images/froala%2F1665655682130-1282501.jpg" style="width: 766px;" class="fr-fic fr-dib">The concept of a protected armadillo robot developed by Elizaveta Shelukhina. When hit by something, the robot rolls into a ball to protect its insides. Photo by Dmitry Grigoryev, ITMO.NEWS&nbsp; &nbsp;<img src="https://s3-us-west-1.amazonaws.com/wevolver-project-images/froala%2F1665655703530-1282502.jpg" style="width: 766px;" class="fr-fic fr-dib">The robotic fish presented at the Robotex youth robotics contect. Image courtesy of the Faculty of Control Systems and Robotics&nbsp; &nbsp;These days, students at the faculty are also developing various robotic animals. For example, Maged Mohamed, a second-year student in the Robotics and Artificial Intelligence Master&rsquo;s program, researches biomimetics to come up with his own prototype of a waterproof fish that will also resist the pressure deep underwater to collect samples of the bottom and water for analysis.&nbsp;<hr>Translated by&nbsp;<a data-saferedirecturl="https://www.google.com/url?q=https://news.itmo.ru/en/profile/30/&source=gmail&ust=1665742142569000&usg=AOvVaw3TxK7CnbdCJBWzW22ae5a2" href="https://news.itmo.ru/en/profile/30/" id="isPasted" rel="noopener noreferrer" target="_blank">Vadim Galimov</a> and <a href="https://news.itmo.ru/en/profile/51/" rel="noopener noreferrer" target="_blank">Catherine Zavodova</a>, and originally published by <a data-saferedirecturl="https://www.google.com/url?q=https://news.itmo.ru/en/&source=gmail&ust=1665742142569000&usg=AOvVaw2LChR-pA6lYpYiNzCB_TIH" href="https://news.itmo.ru/en/" target="_blank">ITMO.NEWS</a>

Boston Dynamics’ Spot, bionic kangaroos and even ants – biomimetics allows us to replicate almost any living thing. But why do roboticists look to animals for inspiration, what do they do at ITMO, and how do you make a robot act “natural”?

Biomimetics: The Science of Robo-Animals

In this episode, we talk about how engineers inspired by some of biology&rsquo;s most miniature wonders (like dandelions&#39; seeds and microorganisms&#39; cilia) are using their knowledge to make major breakthroughs in biosensing, robotics, biomedical engineering, and more. &nbsp;<iframe height="200px" width="100%" frameborder="no" scrolling="no" seamless="" src="https://player.simplecast.com/10c09f29-5a05-4710-b0e0-b25e0d139652?dark=false" class="fr-draggable" data-lf-yt-playback-inspected-kn9eq4roawkarlvp="true"></iframe><hr>This podcast is sponsored by <a href="https://www2.mouser.com/" id="isPasted" rel="nofollow" target="_blank">Mouser Electronics</a>. &nbsp;<img src="https://s3-us-west-1.amazonaws.com/wevolver-project-images/froala%2F1656328852054-Mouser-sponsor-1-a.jpg" style="width: 766px;" class="fr-fic fr-dib"><hr><h3 id="isPasted">EPISODE NOTES</h3>(0:55) - <a href="https://www.wevolver.com/article/inspired-by-dandelion-seeds-these-tiny-battery-free-sensor-systems-ride-the-wind" target="_blank">Dandelion Inspired Sensors</a> 🍃(11:45) - <a href="https://www.wevolver.com/article/self-propelled-endlessly-programmable-artificial-cilia" target="_blank">Microscale Robotic Cilia</a> 🦠<hr>As always, you can find these and other interesting &amp; impactful engineering articles on Wevolver.com.To learn more about this show, please visit our<a href="https://www.wevolver.com/profile/the.next.byte" target="_blank">&nbsp;shows page</a>. By following the page, you will get automatic updates by email when a new show is published. Be sure to give us a follow and review on<a href="https://podcasts.apple.com/nl/podcast/the-next-byte/id1548255861?l=en" target="_blank">&nbsp;Apple</a> podcasts,<a href="https://open.spotify.com/show/6lPPsRtegnivsRUEsQ09R7?si=IPMiah7xT_apJtPjqvXMlA" target="_blank">&nbsp;Spotify</a>, and most of your favorite podcast platforms!

This prototype sensor, pictured by Mark Stone at the University of Washington, disperses itself on the wind and harvests sunlight for energy.

In this episode, we talk about how engineers inspired by some of biology’s most miniature wonders (like dandelions' seeds and microorganisms' cilia) are using their knowledge to make major breakthroughs in biosensing, robotics, biomedical engineering, and more.

Podcast: Size Matters: Tiny Biomimicry Leads to Big Breakthroughs

In this episode, we talk about how ostriches are inspiring a new generation of bipedal robots and the innovation enabling remote endovascular surgery. As always, you can find these and other interesting &amp; impactful engineering articles on Wevolver.com.<iframe height="200px" width="100%" frameborder="no" scrolling="no" seamless="" src="https://player.simplecast.com/e2238814-9212-4010-afb6-ac48d637140f?dark=false" class="fr-draggable" data-lf-yt-playback-inspected-kn9eq4roawkarlvp="true"></iframe><hr>This podcast is sponsored by <a href="https://www2.mouser.com/" id="isPasted" rel="nofollow" target="_blank">Mouser Electronics</a>.&nbsp;<img src="https://s3-us-west-1.amazonaws.com/wevolver-project-images/froala%2F1651565842197-Mouser-sponsor-1-a.jpg" style="width: 766px;" class="fr-fic fr-dib"><hr>(0:50) -&nbsp;<a href="https://www.wevolver.com/article/birdbot-a-3d-printed-bipedal-robot-offers-major-efficiency-gains-through-avian-biomimicry" target="_blank">Using Bird Biology To Make Efficient Walking Robots</a>(20:45) -&nbsp;<a href="https://www.wevolver.com/article/joystick-operated-robot-could-help-surgeons-treat-stroke-remotely" target="_blank">Joystick-operated Robot For Treating Strokes</a>Episode 68 was brought to you by Mouser Electronics, Farbod &amp; Daniel&rsquo;s favorite electronics distributor. Click <a href="https://www.mouser.com/applications/future-robotics-singularity/" target="_blank">here</a> to read the article discussing the merger of technology and humanity.<hr>About the podcast:Every day, some of the most innovative universities, companies, and individual technology developers share their knowledge on Wevolver. To ensure we can also provide this knowledge for the growing group of podcast listeners, we started a collaboration with two young engineers, Daniel Scott Mitchell &amp; Farbod Moghaddam who discuss the most interesting content in this podcast series.&nbsp;To learn more about this show, please visit the <a href="https://www.wevolver.com/profile/the.next.byte" target="_blank">shows page</a>. By following the page, you will get automatic updates by email when a new show is published.Be sure to give us a follow and review on <a href="https://podcasts.apple.com/nl/podcast/the-next-byte/id1548255861?l=en" rel="nofollow" target="_blank">Apple</a> podcasts, <a href="https://open.spotify.com/show/6lPPsRtegnivsRUEsQ09R7?si=IPMiah7xT_apJtPjqvXMlA" rel="nofollow" target="_blank">Spotify</a>, and most of your favorite podcast platforms!Take a few seconds to leave us a review. It really helps! <a href="https://apple.co/2RIsbZ2" rel="nofollow" target="_blank">https://apple.co/2RIsbZ2&nbsp;</a>if you do it and send us proof, we&rsquo;ll give you a shoutout on the show.

The prototype motorized BirdBot, seen here with legs in the locked position, uses a quarter the energy of its immediate predecessor.

In this episode, we talk about how ostriches are inspiring a new generation of bipedal robots and the innovation enabling remote endovascular surgery. 

Podcast: Bird-inspired Bipedal Robots & Robotic Surgeons

This article was discussed in our <a data-saferedirecturl="https://www.google.com/url?q=https://www.wevolver.com/profile/the.next.byte&source=gmail&ust=1651619086659000&usg=AOvVaw31M1Y-wsRw4c0h8-at-VxZ" href="https://www.wevolver.com/profile/the.next.byte" id="isPasted" rel="noopener noreferrer" target="_blank">Next Byte podcast</a>.&nbsp;<iframe height="200px" width="100%" frameborder="no" scrolling="no" seamless="" src="https://player.simplecast.com/e2238814-9212-4010-afb6-ac48d637140f?dark=false" class="fr-draggable" data-gtm-yt-inspected-1_19="true" data-lf-yt-playback-inspected-kn9eq4roawkarlvp="true"></iframe>The full article will continue below.<hr>Watching a bird like an ostrich running reveals a locomotive mechanism far closer to a creature like the mighty Tyrannosaurus Rex than the human leg, and few could doubt its efficacy &mdash; leading a team at the Dynamic Locomotion Group of the Max Planck Institute for Intelligent Systems (MPI-IS) to wonder if current approaches for bipedal robot designs could benefit from being more bird.&ldquo;No current bipedal robot can run quickly, untethered, in natural environments over long distances,&rdquo; the researchers explain in a recently-published paper. &ldquo;However, these activities are commonplace for terrestrial animals. Paradoxically, animals vastly outperform current robots despite considerably slower sensing and information transfer rates.&rdquo;<h1>Inspired by, and defining, nature</h1>Before you can take inspiration from bird locomotion, however, you need to ascertain why it&rsquo;s so effective &mdash; and that&rsquo;s not necessarily an easy task. &ldquo;It&rsquo;s not the nervous system, it&rsquo;s not electrical impulses, it&rsquo;s not muscle activity,&rdquo; claims senior author Alexander Badri-Spr&ouml;witz. &quot;We hypothesized a new function of the foot-leg coupling through a network of muscles and tendons that extends across multiple joints.&ldquo;These multi-joint muscle-tendon coordinate foot folding in the swing phase. In our robot, we have implemented the coupled mechanics in the leg and foot, which enables energy-efficient and robust robot walking. Our results demonstrating this mechanism in a robot lead us to believe that similar efficiency benefits also hold true for birds.&rdquo;<iframe src="https://www.youtube.com/embed/wwH40rYJt9g?&wmode=opaque&rel=0&enablejsapi=1&origin=https://www.wevolver.com" allowfullscreen="" class="fr-draggable" width="640" height="360" frameborder="0" data-lf-yt-playback-inspected-kn9eq4roawkarlvp="true" data-gtm-yt-inspected-1_19="true" id="501349169"></iframe> Dubbed BirdBot, the resulting design is used to prove the team&rsquo;s hypothesis in two directions: firstly that taking inspiration from the leg of a bird can boost the performance of a bipedal robot while simultaneously boosting energy efficiency; and secondly using the resulting robot design to determine the aspects of the leg which contribute most to the efficiency of its living inspiration.Each leg of the BirdBot design uses just two actuator motors, with a traditional third replaced by a clever joint system featuring a joint based on intrinsic engaging and disengaging abilities. As the robot&rsquo;s foot touches the ground and experiences load, the joint system tenses and stiffens to support the weight; as it&rsquo;s lifted off and swung, a bi-stable snap-through joint driven by elastically-stored energy unlocks the leg into a slack configuration.<h1>Simply better</h1>The BirdBot approach comes with a host of improvements over traditional designs, its creators claim. The most immediately obvious: It&rsquo;s electronically simpler, using only two motors and with no need for on-board sensing or complicated control circuitry. Instead, the leg itself handles locking and unlocking automatically &mdash; and can even handle stabilization using a single feed-forward motor command.Its biggest enhancement: Efficiency. Compared to the Cheetah-Cub design published back in 2013, BirdBot requires around a quarter of the energy for locomotion &mdash; putting its performance within the range, its creators say, of &ldquo;an animal of equivalent weight.&rdquo;<img src="https://images.wevolver.com/eyJidWNrZXQiOiJ3ZXZvbHZlci1wcm9qZWN0LWltYWdlcyIsImtleSI6ImZyb2FsYS8xNjQ5ODY0MDM4NzU4LWJpcmRib3QzLmpwZyIsImVkaXRzIjp7InJlc2l6ZSI6eyJ3aWR0aCI6OTUwLCJmaXQiOiJjb3ZlciJ9fX0=" style="width: 300px;" class="fr-fic fr-dib" alt="A picture of the BirdBot prototype, seen next to a diagram making its major parts including knee and hip motors and the tendons which allow it to engage and disengage a clutch-like leg. Further photographs are given of the robot being tested on a treadmill with tethered guidance.">The 3D-printed BirdBot prototype operates with just two motors per leg, relying on a mechanical &quot;clutch&quot; system inspired by birds&#39; legs for the remainder of its operation.&ldquo;Previously, our robots had to work against the spring or with a motor either when standing or when pulling the leg up, to prevent the leg from colliding with the ground during leg swing. This energy input is not necessary in BirdBot&rsquo;s legs,&rdquo; Badri-Spr&ouml;witz, who also led the Cheetah-Cub team, explains.Other advantages claimed in the paper detailing BirdBot&rsquo;s design include the ability to stand upright through torque loading, with all actuators unpowered &mdash; &ldquo;reminiscent,&rdquo; say its creators, &ldquo;of a flamingo standing while sleeping&rdquo; &mdash; and of being highly scalable, with one prototype created during the work standing 1.75m (around 5.7 feet) tall and able to hold the weight of a human being.&ldquo;On the basis of our analysis and physical demonstrations,&rdquo; the team concludes, &ldquo;we suggest that BirdBot&rsquo;s leg design can become a blueprint for large legged machines.&rdquo;<img src="https://images.wevolver.com/eyJidWNrZXQiOiJ3ZXZvbHZlci1wcm9qZWN0LWltYWdlcyIsImtleSI6ImZyb2FsYS8xNjQ5ODY0MDUyNDkwLWJpcmRib3Q0LmpwZyIsImVkaXRzIjp7InJlc2l6ZSI6eyJ3aWR0aCI6OTUwLCJmaXQiOiJjb3ZlciJ9fX0=" style="width: 300px;" class="fr-fic fr-dib" alt="Photographs showing the small BirdBot prototype next to an unpowered large-scale 1.75m version based on the same principles. A researcher is seen placing his weight on the leg in its standing position, then stepping off to the floor and lifting the leg to its swinging position.">A large-scale version of the leg proved capable of holding the weight of an adult human &mdash; and its creators say it could be scaled up still further.That&rsquo;s not to say their work is finished, however. The current motorized BirdBot prototype, which uses off-the-shelf actuators fitted to a 3D-printed trunk and legs, has been tested on a treadmill with tethered guidance.To create a version capable of standing freely and moving in three dimensions will require further research to prevent pitching, potentially involving a revised design or a shift to hip-only actuation. While operable without sensor input, the team also suggests that an investigation into how the clutch mechanism could be used alongside direct actuation and sensory feedback control to &ldquo;merge the benefits of both systems.&rdquo;The team&rsquo;s work has been published in the journal <a href="https://www.science.org/doi/10.1126/scirobotics.abg4055" target="_blank"><cite>Science Robotics</cite></a>, with an open-access version available via author referral <a href="https://is.mpg.de/publications/bb01" target="_blank">on the MPI publication page</a>.<h1>References</h1>Alexander Badri-Spr&ouml;witz, Alborz Aghamaleki Sarvestani, Metin Sitti, and Monica A. Daley: <cite>BirdBot achieves energy-efficient gait with minimal control using avian-inspired leg clutching, Science Robotics Vol. 7 Iss. 64</cite>. DOI <a href="https://doi.org/10.1126/scirobotics.abg4055" target="_blank">10.1126/scirobotics.abg4055</a>.Alexander Badri-Spr&ouml;witz (as Alexander Spr&ouml;witz), Alexandre Tuleu, Massimo Vespignani, Mostafa Ajallooeian, Emilie Badri, and Auke Jan Ijspeert: <cite>Towards dynamic trot gait locomotion: Design, control, and experiments with Cheetah-cub, a compliant quadruped robot, The International Journal of Robotics Research Vol. 32 Iss. 8</cite>. DOI <a href="https://doi.org/10.1177/0278364913489205" target="_blank">10.1177/0278364913489205</a>.

Created by the Dynamic Locomotion Group at the Max Planck Institute for Intelligent Systems (MPI-IS), BirdBot serves two purposes: Demonstrating a more efficient bipedal robot design, and furthering our understanding of how birds' legs work.

BirdBot, a 3D-printed bipedal robot, offers major efficiency gains through avian biomimicry

The next step in machine learning, how 3D printing will change the airline industry, and why flies hold the secret to robotic flight. As always, you can find these articles and other interesting engineering content on Wevolver.com.&nbsp;<iframe height="200px" width="100%" frameborder="no" scrolling="no" seamless="" src="https://player.simplecast.com/f6b5e009-6f76-413b-a49b-032c4fc123db?dark=false" class="fr-draggable" data-lf-form-tracking-inspected-kn9eq4roawkarlvp="true" data-lf-yt-playback-inspected-kn9eq4roawkarlvp="true" data-lf-vimeo-playback-inspected-kn9eq4roawkarlvp="true"></iframe><h2 data-v-1111b158="" data-v-8334d7b8="">Episode Notes</h2><div data-v-1111b158="" data-v-8334d7b8="">(0:40) The next stop in machine learning: making sense of abstract concepts -&nbsp;Researchers from MIT, IBM, and Columbia created a machine learning model that exhibits abstract reasoning.&nbsp;(6:00) How additive manufacturing can shift manufacturing methodologies in the airline industry -&nbsp;EOS and other 3D printing companies are changing the airline industry’s manufacturing methods, starting with interiors.(12:15) Can flies hold the secret to enable enhanced robotic flight? -&nbsp;Penn State researchers crack the code to improve robotic flight by studying the behavior of fruit flies.&nbsp;&nbsp;--About the podcast:Every day, some of the most innovative universities, companies, and individual technology developers share their knowledge on Wevolver. To ensure we can also provide this knowledge for the growing group of podcast listeners, we started a collaboration with two young engineers, Daniel Scott Mitchell &amp; Farbod Moghaddam who discuss the most interesting content in this podcast series.&nbsp;To learn more about this show, please visit the&nbsp;<a href="https://www.wevolver.com/profile/the.next.byte" target="_blank">shows page</a>. By following the page, you will get automatic updates by email when a new show is published.Be sure to give us a follow and review on&nbsp;<a href="https://podcasts.apple.com/nl/podcast/the-next-byte/id1548255861?l=en" target="_blank">Apple</a> podcasts,&nbsp;<a href="https://open.spotify.com/show/6lPPsRtegnivsRUEsQ09R7?si=IPMiah7xT_apJtPjqvXMlA" target="_blank">Spotify</a>, and most of your favorite podcast platforms!</div>

The next step in machine learning, how 3D printing will change the airline industry, and why flies hold the secret to robotic flight.

Podcast: Abstract Machine Learning, 3D Printing Airplanes, Learning Flight From Flies

Orthopaedic cast immobilisation is one of the most common ways to treat broken and fractured bones. This process involves the use of materials to encase and restrict the movement of broken bones, allowing them to heal.As technology has become more accessible, 3D Printed casts have grown in popularity. They are much lighter, more comfortable and easier to produce than traditional casts. Despite the evolution in cast production qualities, all casts share a fundamental flaw – they are single-use products.Since the job of a cast is to set body parts in a fixed position, they have to be tailor-made to the unique anatomy of the individual patients.3D printed casts are also complex in their structure, these factors eliminate the possibility of reusing casts, even if hygiene issues were non-existent.&nbsp;CREATE Education Ambassador, <a href="https://www.createeducation.com/community-partner/jack-cockle/" target="_blank">Jack Cockle</a> identified an opportunity to explore alternative strategies to make immobilisation casts more sustainable. With an aim to reduce the inevitable waste generated by their complex and tailored form and maintenance of hygiene standards. <img class="fr-fic fr-dib" src="https://images.wevolver.com/eyJidWNrZXQiOiAid2V2b2x2ZXItcHJvamVjdC1pbWFnZXMiLCAia2V5IjogImZyb2FsYS8xNjA0NDg3NDY4NDE4LUpDUzUuanBnIiwgImVkaXRzIjogeyJyZXNpemUiOiB7IndpZHRoIjogOTUwLCAiZml0IjogImNvdmVyIn19fQ==" style="width: 300px;"><h1 dir="ltr">The Process</h1>As part of one of Jack’s final year projects whilst studying BA (Hons) Sustainable Product Design, he began by making a normal plaster cast, trialling traditional methods of the cast making to justify future design choices.Then making a basic 3D printed cast, by scanning his hand/arm using a 3D scanner and software. Exporting the scan as an STL file into <a href="https://marketplace.createeducation.com/product/fusion-360-software-training/" target="_blank">Autodesk Fusion 360</a>, which was then converted to a b-rep file, allowing Jack to model a form around the hand/arm.Next, 3D printing the cast in <a href="https://marketplace.createeducation.com/?swoof=1&post_type=product&pa_material=petg&paged=1" target="_blank">rPETG</a> on the <a href="https://marketplace.createeducation.com/product/ultimaker-s5-3d-printer/" target="_blank">Ultimaker S5</a>. This was made easier by the scale of the printer, saving time where Jack would have had to split up the model into more pieces, then glueing them together.&nbsp;To explore the scope of making casts more sustainable, Jack evaluated multiple design ideas through an iterative process. The aim was to investigate the possibility of fabricating 3D printed casts that adapt to the form of the user, rather than existing as a rigid form tailored to individual patients, thus making them more suitable for reuse.This idea came to Jack as his colleagues tried on the 3D printed cast, which almost, but didn’t perfectly fit them due to the varied shapes of individuals' limbs.Owing to Auxetic materials and structures exhibiting certain abnormal mechanical responses, thanks to the possession of negative Poisson’s ratio response. Meaning they get thicker when stretched lengthwise and thinner when compressed. Jack began experimenting with auxetic forms in different materials such as <a href="https://marketplace.createeducation.com/product-category/filament/?swoof=1&paged=1&pa_material=tpu&really_curr_tax=812-product_cat" target="_blank">TPU</a> and Flexible Resin.<img class="fr-fic fr-dib" src="https://images.wevolver.com/eyJidWNrZXQiOiAid2V2b2x2ZXItcHJvamVjdC1pbWFnZXMiLCAia2V5IjogImZyb2FsYS8xNjA0NDg4NTU1MjYyLTMwMGRwaUR5bmFtaUNhc3QzLmpwZyIsICJlZGl0cyI6IHsicmVzaXplIjogeyJ3aWR0aCI6IDk1MCwgImZpdCI6ICJjb3ZlciJ9fX0=" style="width: 300px;"> In Rhino3D, Jack generated a series of cylindrical auxetic lattice forms, choosing the ones that required no support material (as this would be difficult to remove from such a complex structure). Jack printed them in both TPU and flexible resin to test how well each structure and material compressed under pressure.The concept was a flexible resin auxetic sleeve that fits over the arm of the patient, which is compressed by the rigid PETg shell, immobilising the limb.In theory, the reusable cast would reduce waste, cut lead times (as a stock of casts could be kept) and the longer-term cost of casts per patient (since the costs of one cast could be distributed across several patients).Jack has been developing the mesh further, to become elastic resin bands that are finer, have more layers, and are preinstalled into the cast shell before being applied to the arm. <img class="fr-fic fr-dib" src="https://images.wevolver.com/eyJidWNrZXQiOiAid2V2b2x2ZXItcHJvamVjdC1pbWFnZXMiLCAia2V5IjogImZyb2FsYS8xNjA0NDg5Mzc1NzUyLTMwMGRwaUR5bmFtaUNhc3QyICgxKS5qcGciLCAiZWRpdHMiOiB7InJlc2l6ZSI6IHsid2lkdGgiOiA5NTAsICJmaXQiOiAiY292ZXIifX19" style="width: 300px;"><hr><h2 dir="ltr">Do you want to CREATE the Future of Education?</h2>Industry is adopting additive manufacturing at an exponential rate, it is critical to be equipped with the skills needed in employment.&nbsp;It is imperative that individuals experience these ground-breaking technologies today, to futureproof UK manufacturing in a globally competitive marketplace and address the many global issues we face.CREATE Education are expert providers across the UK and Ireland, specialising in developing 3D technologies in education, to enable learners and empower educators.&nbsp;Get in touch with our education specialists today on 01257 276 116 or email us at&nbsp;<a href="mailto:enquiries@createeducation.com" target="_blank">enquiries@createeducation.com</a>.

Further harnessing 3D printing technology to promote sustainability within the medical industry

As technology has become more accessible, 3D Printed casts have grown in popularity,  owing to several benefits. However, all casts share a fundamental flaw - they are single-use products

3D Printing Sustainable Casts

I know what you are thinking: cellular materials and lightweighting? Who made this guy a Professor? I hear you. While my students and I have spent a lot of time the past four years studying cellular materials, it has been in the context of energy absorption, honeycomb panel design, capillary action, and thermal management, and not with the intent to lightweight (is it now ok to use it as a verb?) a structure. However, when nTopology approached me with a request to contribute to a series of talks on lightweighting, I wondered if this was a good time to enter the dark dungeon and chat with the trolls. The result of my explorations is this blog post, and the accompanying webinar, that I hope will spark some ideas, if not justify my hiring.Traditional approaches to lightweighting involve material selection, consolidation, and topology optimization (Figure 1). Design solutions are of particular importance when working with higher density metals where composition is selected for reasons such as high temperature performance or corrosion resistance, and the door to lower-density materials is closed. Cellular materials such as lattices and foams are typically not thought of as leading design candidates for lightweighting, and skepticism in this area is well founded. There are several reasons for this, most fundamentally perhaps being the point that the very requirement of structure to have cellularity is in itself a limiting constraint from a design optimization standpoint. Nonetheless, I would like to stick my neck out and examine if this always must be the case.<img src="https://images.wevolver.com/eyJidWNrZXQiOiJ3ZXZvbHZlci1wcm9qZWN0LWltYWdlcyIsImtleSI6ImZyb2FsYS8xNjAxMjI1MDc0NjI1LWZpZ3VyZS0xLWRiLnBuZyIsImVkaXRzIjp7InJlc2l6ZSI6eyJ3aWR0aCI6OTUwLCJmaXQiOiJjb3ZlciJ9fX0=">Figure 1: Traditional approaches to lightweighting include (a) material selection, (b) consolidation, and (c) topology optimization [Photo credits – (a): CES EduPack 2018, Granta Design Ltd., (b) and (c): nTopology]&nbsp;The first argument for why we need to consider cellular materials in the context of lightweighting, and one I will focus in this blog post, is the argument from nature. We do find cellular structures in biological structure (Figure 2), such as insect nests, turtle shells, bone, and sea urchin spines, where mass minimization is always an inherent requirement. In some cases, such as the beaks and bones of birds, lightweighting is critical. As the songwriter J.J. Cale put it, “Travelin’ light is the only way to fly.” Fortunately he gives us no details about how this is to be accomplished, which is why engineers like you and me still have jobs in this world, and care enough to write and read (?) blog posts.&nbsp;<img src="https://images.wevolver.com/eyJidWNrZXQiOiJ3ZXZvbHZlci1wcm9qZWN0LWltYWdlcyIsImtleSI6ImZyb2FsYS8xNjAxMjI1MDk3NjI4LWZpZ3VyZS0yLWRiLnBuZyIsImVkaXRzIjp7InJlc2l6ZSI6eyJ3aWR0aCI6OTUwLCJmaXQiOiJjb3ZlciJ9fX0=">Figure 2: Natural structures where minimizing weight is of importance, and also exhibit cellular material design: (a) Venation of a water lily leaf, (b) wasp nest, (c) trabecular bone [Photo Credits: Wikimedia Commons (a) Laitr Keiows; (c) Neon]&nbsp;This apparent paradox can be resolved by making the argument that there are (at least) three performance objectives, which when sought, strengthen the candidacy of cellular materials for lightweighting: surface and volume infilling, multi-functionality, and damage tolerance. We find these demonstrated in natural structure, but also in engineering applications that embody cellular materials for these reasons, including honeycomb core commonly used in panels. These insights can be leveraged to inform engineering design of lightweight structures, and implemented by leveraging a framework for cellular material design that consists of four concepts: discretization, periodicity, gradients, and hierarchy. These concepts lend themselves very well to study in the context of nTopology’s equation-based implicit modeling platform (small p intended). One example of this is work done by one of my students using nTopology to create different geometries to study the effect of aperiodicity (Figure 3).&nbsp;<img src="https://images.wevolver.com/eyJidWNrZXQiOiJ3ZXZvbHZlci1wcm9qZWN0LWltYWdlcyIsImtleSI6ImZyb2FsYS8xNjAxMjI1MTIyMDAyLWZpZ3VyZS0zLWRiLnBuZyIsImVkaXRzIjp7InJlc2l6ZSI6eyJ3aWR0aCI6OTUwLCJmaXQiOiJjb3ZlciJ9fX0=">Figure 3: Use of nTopology to develop cellular material designs with varying degrees of aperiodicity [Photo Credits: Daniel Anderson, 3DX Research, ASU]&nbsp;Lest I be accused of “having a hammer and looking for a nail”, which while fair, is not the entire story, I would like to end by clarifying that cellular materials merely represent an alternative for lightweighting when the performance objectives mentioned previously are also being sought. However, I will go a step further and speculate that cellular material design is a critical element at the frontier of lightweighting since it helps us enable true multi-functional, material-and-structure co-optimization at a range of scales. Of course at this point, cellular design and other techniques blend into each other, and the boundaries between formal approaches to lightweighting start to break down. This is my second argument for why we need to consider cellular materials for lightweighting: they tie everything together. How am I so sure? Because life, uh, has found a way.&nbsp;<hr><h3>References</h3><ol><li>Harris, “Five Techniques for Lightweighting: Doing More With Less,” January 2020, <a href="https://www.techbriefs.com/component/content/article/tb/pub/features/articles/35824" target="_blank">https://www.techbriefs.com/component/content/article/tb/pub/features/articles/35824</a></li><li>du Plessis, C. Broeckhoven, I. Yadroitsava, I. Yadriotsev, C. Hands, R. Kunju, D. Bhate, “Beautiful and Functional: A Review of Biomimetic Design in Additive Manufacturing,” Additive Manufacturing, Volume 27, pages 408-427, May 2019</li><li>Bhate, C. Penick, L. Ferry, C. Lee, “Classification and Selection of Cellular Materials in Mechanical Design: Engineering and Biomimetic Approaches,” Invited paper, Special Issue on Advances in Biologically Inspired Design, MDPI Designs, 3(1), 19, 2019</li><li>J. Cale, “Travelin’ Light”, Troubadour, Shelter Records, 1976</li><li>Malcolm, “Jurassic Park,” Universal Studios, 1993</li></ol><hr>This article was first published on the <a href="https://ntopology.com/blog/2020/08/21/lightweighting-with-cellular-materials-insights-from-nature/" rel="noopener noreferrer" target="_blank">nTopology blog.</a>

Can cellular materials serve as a design solution for achieving lightweighting of engineering structures? Let’s listen to what nature has to say.

Lightweighting with Cellular Materials: Insights from Nature

<h2>Akira Science AB, a start-up based in Stockholm, is betting on the combination of two revolutionary disciplines: tissue engineering and 3D printing.&nbsp;</h2>These two disciplines used to belong to two different stories that are now deeply interconnected. During the last fifty years scientists and surgeons have combined the concepts of life sciences, biology and biocompatible materials to construct functional tissues and open the way to innovative and less invasive techniques respect to traditional surgical transplants. They have been looking for new materials to substitute classical treatments to improve medical treatments where autograph or allograph of explanted tissues are required due to disease or trauma. In parallel to this story, 3D printing technologies also known as Additive Manufacturing (AM) were born in the 1980s and initially intended to quickly produce prototypes within industrial applications. When 3D printing technologies later met tissue engineering, a powerful combination consolidated to create structures with controlled geometry and high rate of reproducibility. Tissue engineers have been seeking for structures &ndash; scaffolds&nbsp;&ndash; that can provide structural and mechanical support to a damaged tissue while promoting its regeneration and allowing nutrients&rsquo; supply to the cells.The 3D printing market has been growing fast during the last decade releasing innovative technologies and materials, especially for the medical sector. 3D printing is transforming the way we manufacture objects from a centralized to a decentralized, customized production onsite.Akira Science is projected to have an active role in these future landscapes of smart and innovative manufacturing technologies applied to degradable materials for medical applications. The business potential arises from the ever-increasing need of patient-specific medical devices and of timely laboratory biological studies to test drugs and new clinical strategies - never so evident like in this pandemic period.&nbsp;<img src="https://s3-us-west-1.amazonaws.com/wevolver-project-images/froala%2F1590050859860-1590050859859.png" style="width: 655px;" class="fr-fic fr-dib">A cutting-edge new material and a smart scaffold design are the complementary and revolutionary points of force of Akira&rsquo;s strategy. The newly developed polymer (AKIMed-c12) has exceptional thermal stability, ensuring control of the material properties while printing, presenting a faster degradation time in the body environment than the current utilized materials (from 3-5 years to 9-10 months). Although newly formulated, AKIMed-c12 is made starting from well-established building blocks for the synthesis of approved biomedical materials, ensuring biocompatibility and non-toxicity in the physiological environment. While the printed scaffolds are not hard as the current available ones, but soft and pliable proving comfort to the patient (AKIMed-c12: 3D printed scaffolds).<iframe width="640" height="360" src="https://www.youtube.com/embed/GdgRqw2ZHjw?&wmode=opaque" frameborder="0" allowfullscreen="" class="fr-draggable"></iframe> The new material will be the workhorse for the 3D printing of degradable medical devices, while the smart design opens the way to new applications in tissue regeneration that were not possible until today utilizing the materials available on the market. Akira team is confident that such a combination has the potential to expand the scope of degradable 3D printed scaffolds from hard, for example bone, to soft tissue regeneration, such as breast reconstruction after mastectomy.Akira Science is providing both filaments for 3D printing and scaffolds with an architecture that satisfies customers&rsquo; need. Researchers and clinicians can buy the filament (AKIMed-c12: filament) and print the desired shape in their own facilities or can decide to ask Akira for printing their customized devices. Akira also provides support and consulting to collaborators and customers with material selection, design and simulation of the mechanical behavior of the desired scaffolds.The company continues to invest in open innovation through a continuous dialogue with customers and by setting new strategies to map future needs in tissue engineering and 3D printing opportunities.<hr>&Aacute;lvaro Morales and Tiziana Fuoco (AKIRA Science AB)